The impact of ibidi products on the global application of science is highlighted in more than 21.000 peer-reviewed publications
Cell migration occurs during many important physiological processes. For example, controlled cell migration allows for embryonic development, tissue injury, and wound healing. In contrast, cell migration is dysregulated in many pathological situations, such as cancer metastasis and inflammation. Not surprisingly, the principles behind cell migration have been studied in many contexts.
In our body, endothelial cells are surrounded by the basement membrane, which is a thin and highly specialized extracellular matrix (ECM). When endothelial cells, such as human umbilical vein cells (HUVECs), are seeded onto a basement membrane-like surface (e.g., Matrigel®) they form capillary-like structures in vitro, which recapitulates angiogenesis.
A chemotaxis assay is conducted to analyzewhether or not a cell type directly orients and migrates towards a defined chemoattractant. Since chemotaxis is a particularly important process during cancer development and immune infiltration, frequently used cell types in chemotaxis assays are cancer cells and immune cells.
Live cell imaging is the time-lapse microscopy of dynamic processes in living cells. It enables observation of cell-cell interactions, the behavior of single cells, and the dynamics of cell organelles or cellular molecules. Several imaging techniques can be applied, such as phase contrast microscopy, fluorescence and confocal microscopy, multiphoton microscopy, light sheet microscopy, or even TIRF and super-resolution microscopy.
The outstanding characteristic of the ibidi µ-Slides, µ-Dishes, and µ-Plates is their thin coverslip bottom, which has excellent features for high-end microscopy applications. ibidi offers labware with the ibidi Polymer Coverslip bottom or the ibidi Glass Coverslip bottom.
Consultio comes with a beautiful collection of modern, easily importable, and highly customizable demo layouts. Any of which can be installed via one click.